Alcohol-induced facial dysmorphology in C57BL/6 mouse models of fetal alcohol spectrum disorder
نویسندگان
چکیده
منابع مشابه
Callosal thickness reductions relate to facial dysmorphology in fetal alcohol spectrum disorders.
BACKGROUND Structural abnormalities of the corpus callosum (CC), such as reduced size and increased shape variability, have been documented in individuals with fetal alcohol spectrum disorders (FASD). However, the regional specificity of altered CC structure, which may point to the timing of neurodevelopmental disturbances and/or relate to specific functional impairments, remains unclear. Furth...
متن کاملRegional brain volume reductions relate to facial dysmorphology and neurocognitive function in fetal alcohol spectrum disorders.
Individuals with heavy prenatal alcohol exposure can experience significant deficits in cognitive and psychosocial functioning and alterations in brain structure that persist into adulthood. In this report, data from 99 participants collected across three sites (Los Angeles and San Diego, California, and Cape Town, South Africa) were analyzed to examine relationships between brain structure, ne...
متن کاملPrenatal Alcohol Use and Fetal Alcohol Spectrum Disorder in Indiana
Maternal alcohol use during pregnancy can have deleterious effects. Alcohol in the mother’s blood passes through the placenta to the embryo and fetus via the umbilical cord, and may cause numerous problems, including developmental delays, growth impairment, and a variety of behavioral changes [1]. Compared to all other substances of abuse, including heroin, cocaine, and marijuana, alcohol produ...
متن کاملFacial dysmorphism across the fetal alcohol spectrum.
OBJECTIVE Classic facial characteristics of fetal alcohol syndrome (FAS) are shortened palpebral fissures, smooth philtrum, and thin upper vermillion. We aim to help pediatricians detect facial dysmorphism across the fetal alcohol spectrum, especially among nonsyndromal heavily exposed (HE) individuals without classic facial characteristics. METHODS Of 192 Cape Coloured children recruited, 69...
متن کاملFetal alcohol spectrum disorder in Israel.
BACKGROUND Fetal alcohol spectrum disorder is a range of disabilities caused by gestational exposure to alcohol. FASD is the leading cause of preventable mental retardation and developmental disability in the United States, with an incidence of 1-10 per 1000 live births. FASD in Israel has yet to be examined systematically. OBJECTIVES To evaluate professionals' experience, awareness and knowl...
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ژورنال
عنوان ژورنال: Alcohol
سال: 2010
ISSN: 0741-8329
DOI: 10.1016/j.alcohol.2010.04.002